TMU 35435 - CAS 2231800-32-9

TMU 35435 is an inhibitor of histone deacetylases (HDAC) . It enhances radiosensitivity by inducing the accumulation of misfolded proteins and autophagy (autophagy) in TNBC, and inhibits the NHEJ pathway through ubiquitination of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) .

Autophagy, HDAC

Autophagy, DNA Damage/DNA Repair, Chromatin/Epigenetic

2231759

C22H25N3O3

379.45

O=C(NCCCCCCC(=O)NO)C1=CC=CC=2C=C3C=CC=C(C3=NC21)C

-20°C

Ice Packs

Small Compound