TMX-2039 - CAS 2488892-01-7

TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.

Ligands for Target Protein for PROTAC, CDK

PROTAC, Cell Cycle/Checkpoint

2488892-01-7

C17H20BrFN6O3S

487.347

O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3CCN(CC3)S(=O)(=O)C

-20°C

Ice Packs

PROTAC