TMX-4116 - CAS 2766385-56-0

TMX-4116 is a casein kinase 1α (CK1α) degrader that preferentially targets CK1α for degradation in cell lines including MOLT4, Jurkat, and MM.1S. TMX-4116 exhibits potent activity with degradation concentration 50 values (DC50s) below 200 nM. TMX-4116 is employed in the study of multiple myeloma and protein degradation strategies.

Molecular Glues, Casein Kinase

Stem Cells, PROTAC, Metabolism

2766329

C17H19N5O4S

389.43

O(C)C=1C(=CSC1C(=O)N2CCCC2)C3=CN(N=N3)C4C(=O)NC(=O)CC4

-20°C

Ice Packs

PROTAC