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TNIK&MAP4K4-IN-1 - CAS 2478592-86-6

TNIK&MAP4K4-IN-1 - CAS 2478592-86-6

MF-0157463-01

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Product Details

  • Bioactivity

    TNIK&MAP4K4-IN-1 (compound A-39) is a potent dual inhibitor of TNIK and MAP4K4/HGK, with IC50 values of 1.29 nM and <10 nM, respectively, in human hepatic stellate cell LX-2, and is applicable in cancer and fibrosis inhibition [1].

  • Target

    Others, MAPK

  • Related Pathways

    Others, MAPK

  • CAS Number

    2478500

  • Molecular Formula

    C25H23FN4O3

  • Molecular Weight

    446.47

  • SMILES

    C(NC=1C(OC)=CN=CC1)(=O)C=2OC(C3=C(N=CN3C4CCCC4)C5=CC=C(F)C=C5)=CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound