TNKS-2-IN-1 - CAS 4765-59-7

TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.

PARP, Wnt/beta-catenin, Antibiotic

DNA Damage/DNA Repair, Chromatin/Epigenetic, Cytoskeletal Signaling, Microbiology/Virology, Stem Cells

4699

0.984

C14H9N3O3

267.24

[O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1

-20°C

Ice Packs

Small Compound