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Toddaculin - CAS 4335-12-0
Toddaculin - CAS 4335-12-0
SKU:MF-0011830-01
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Product Details
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Bioactivity
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis inducer in U-937 cells.
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Target
Apoptosis, Others
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Related Pathways
Apoptosis, Others
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CAS Number
4335-12-0
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Purity
0.9991
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Molecular Formula
C16H18O4
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Molecular Weight
274.31
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SMILES
COc1cc2oc(=O)ccc2c(OC)c1CC=C(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product