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Molfinity

Tofacitinib - CAS 477600-75-2

Tofacitinib - CAS 477600-75-2

MF-0045063-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    Tofacitinib (Tasocitinib) is a Janus kinase inhibitor that inhibits JAK3/2/1 (IC50=1/20/112 nM) and is orally active. Tofacitinib is used for the treatment of moderate to severe rheumatoid arthritis.

  • Target

    Apoptosis, ROCK, JAK, Src

  • Related Pathways

    Cell Cycle/Checkpoint, JAK/STAT signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis, Stem Cells, Apoptosis

  • CAS Number

    477523

  • Purity

    >99.99%

  • Molecular Formula

    C16H20N6O

  • Molecular Weight

    312.37

  • SMILES

    C[C@@H]1CCN(C[C@@H]1N(C)C1=C2C=CNC2=NC=N1)C(=O)CC#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound