Tonabersat - CAS 175013-84-0

Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that regulates cellular communication between trigeminal ganglion neuronal cells and glial cells and inhibits neurogenic inflammation for the treatment of migraine and epilepsy.

Gap Junction Protein

Cytoskeletal Signaling

174929

0.9949

C20H19ClFNO4

391.82

N(C(=O)C1=CC(Cl)=C(F)C=C1)[C@H]2C=3C(OC(C)(C)[C@H]2O)=CC=C(C(C)=O)C3

-20°C

Ice Packs

Small Compound