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Tonantzitlolone - CAS 845811-30-5
Tonantzitlolone - CAS 845811-30-5
SKU:MF-0143400-01
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Product Details
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Bioactivity
Tonantzitlolone is a natural agonist of tprc1/4/5 channels, also acting as a dual pkcα and pkcθ activator, inducing an insulin resistant phenotype by inhibiting irs1 and the pi3k/akt pathway, activating the heat shock factor 1 (hsf1) transcription factor driving glucose dependency
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Target
Others
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Related Pathways
Others
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CAS Number
845776
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Molecular Formula
C26H40O7
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Molecular Weight
464.59
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SMILES
O[C@@]12[C@H](OC(/C=C(/CC)\C)=O)[C@H](C)C[C@@](O1)(C(=O)[C@@H](C)/C=C/C(C)(C)[C@]3(O[C@@](C)([C@@H]2O)CC3)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound