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Topi MF-6 - CAS 2944016-96-8
Topi MF-6 - CAS 2944016-96-8
SKU:MF-0118571-01
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Product Details
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Bioactivity
Topi MF-6 is a DNA topoisomerase I (Top1) inhibitor with excellent cytotoxic properties against gastrointestinal cancer cells. It can be utilized as an ADC payload.
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Target
Others, Topoisomerase
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Related Pathways
Others, DNA Damage/DNA Repair
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CAS Number
2943912
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Molecular Formula
C23H19F2N3O4
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Molecular Weight
439.41
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SMILES
FC1(F)C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(N)=CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound