Topiramate lithium - CAS 488127-53-3

Topiramate lithium (McN 4853) is a broad-spectrum antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action includes enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]

Others, GABA Receptor, Carbonic Anhydrase, Calcium Channel, Potassium Channel, Sodium Channel, iGluR

Others, Membrane transporter/Ion channel, Metabolism, Neuroscience

488071

C12H20LiNO8S

345.29

[Li+].CC1(C)O[C@@H]2CO[C@@]3(COS([NH-])(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

-20°C

Ice Packs

Small Compound