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TOPK-p38/JNK-IN-1 - CAS 2745108-35-2

TOPK-p38/JNK-IN-1 - CAS 2745108-35-2

MF-0020195-01

$1,383.80 USD
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Product Details

  • Bioactivity

    TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, exhibiting an IC50 of 2.14 μM for NO production inhibition. It demonstrates anti-inflammatory properties by inhibiting downstream protein phosphorylation and preventing TOPK degradation [1].

  • Target

    JNK, Others

  • Related Pathways

    MAPK, Others

  • CAS Number

    2745108-35-2

  • Molecular Formula

    C17H15F3N2O4

  • Molecular Weight

    368.31

  • SMILES

    N(C(NC1=CC(C(F)(F)F)=CC=C1)=O)C2=C(OC)C=C(O)C(C(C)=O)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound