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Topoisomerase I inhibitor 2 - CAS 2588211-44-1

Topoisomerase I inhibitor 2 - CAS 2588211-44-1

MF-0141041-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Topoisomerase I inhibitor 2 (ZML-8) is a highly selective DNA topoisomerase I (Top1) inhibitor that impedes Top1 activity, causing DNA damage. It arrests the cell cycle at the G2/M phase and induces apoptosis, exhibiting anti-tumor effects [1].

  • Target

    Topoisomerase, Caspase, Apoptosis, Others

  • Related Pathways

    Proteases/Proteasome, Apoptosis, Others, DNA Damage/DNA Repair

  • CAS Number

    2588166

  • Molecular Formula

    C18H15NO3

  • Molecular Weight

    293.32

  • SMILES

    O(C)C=1C=C2C=C3C=4C(OCC3=NC2=CC1OC)=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound