Topoisomerase I inhibitor 4 - CAS 2485135-31-5

Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity, effectively inhibiting the proliferation of various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].

Others, Topoisomerase

DNA Damage/DNA Repair, Others

2485099

C23H19FN4O

386.42

O=C1N2C(C=3C(C2)=CC=4C(C3)=CC=CC4)=NC=5C1=CC(F)=C(C5)N6CCNCC6

-20°C

Ice Packs

Small Compound