Topoisomerase IIα-IN-2 - CAS 2407521-90-6

Topoisomerase IIα-IN-2 (compound 5) is a potent inhibitor of the topoisomerase TopoIIα and a DNA-binding ligand. It exhibits high anti-proliferative activity in human cancer cell lines, arrests the cell cycle in the G2/M phase, and significantly induces DNA damage.

Others, Topoisomerase

DNA Damage/DNA Repair, Others

2407425

C22H20N4O5

420.42

O=C1C=2C(C=3C(OC=4C(N3)=CC=C(C(NCCCC[C@@H](C(O)=O)N)=O)C4)=C1)=CC=CN2

-20°C

Ice Packs

Small Compound