Topoisomerase II inhibitor 18 - CAS 2382959-65-9

Topoisomerase II inhibitor 18 (Compound IV), a Quinoxaline derivative, exhibits an IC 50 of 7.5 μM in inhibiting topoisomerase II. It impedes PC-3 cell proliferation, arrests the cell cycle at the S phase, and induces apoptosis. Moreover, this compound demonstrates substantial antitumor activity against cancer [1].

Topoisomerase

DNA Damage/DNA Repair

2382959-65-9

C20H21N3OS

351.47

S(CCC(NCCC)=O)C=1C(=NC2=C(N1)C=CC=C2)C3=CC=CC=C3

-20°C

Ice Packs

Small Compound