Topoisomerase inhibitor 6 - CAS 2987726-03-2

Topoisomerase inhibitor6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV, with an MIC of 0.06 μg/mL against fluoroquinolone-resistant S. aureus. It halts the DNA strand breaking-rejoining process, causing lethal DNA damage, and holds potential for studying infections caused by Gram-positive bacteria such as S. aureus and S. pneumoniae.

Topoisomerase, Antibacterial

DNA Damage/DNA Repair, Microbiology/Virology

2987726-03-2

C20H22ClFN4O2

404.87

ClC1=C2C(C3=C(C(=O)N2C4CC4)N=C(C)O3)=CC(F)=C1N5C[C@]([C@H](C)N)(CC5)[H]

-20°C

Ice Packs

Small Compound