Topoisomerase IV inhibitor 2 - CAS 2883403-36-7

Topoisomerase IV inhibitor 2 (compound 5d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.35 μM for TOPO IV and 0.55 μM for DNA gyrase. It demonstrates antibacterial properties with minimum inhibitory concentrations (MICs) of 1.985 μM against Staphylococcus aureus Newman and 0.744 μM against Escherichia coli ATCC8739 [1].

Topoisomerase, Antibacterial

DNA Damage/DNA Repair, Microbiology/Virology

2883360

C33H30FN7O6S

671.7

C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCN(CC4)CC(=O)NC5=CC=C(C=C5)S(=O)(=O)NC6=NC7=CC=CC=C7N=C6)F)C(=O)O

-20°C

Ice Packs

Small Compound