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Molfinity

Torin 2 - CAS 1223001-51-1

Torin 2 - CAS 1223001-51-1

MF-0040424-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    Torin 2 (IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 28 nM/35 nM/118 nM, respectively.

  • Target

    DNA-PK, Apoptosis, mTOR, ATM/ATR, Autophagy

  • Related Pathways

    DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Autophagy, Apoptosis

  • CAS Number

    1222949

  • Purity

    0.9947

  • Molecular Formula

    C24H15F3N4O

  • Molecular Weight

    432.4

  • SMILES

    Nc1ccc(cn1)-c1ccc2ncc3ccc(=O)n(-c4cccc(c4)C(F)(F)F)c3c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound