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TP-064 - CAS 2080306-20-1
TP-064 - CAS 2080306-20-1
SKU:MF-0013770-01
Regular price
$33.92 USD
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$33.92 USD
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Product Details
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Bioactivity
TP-064 is a potent and selective PRMT4 inhibitor, featuring an IC50 < 10nM for methylation of H3 (1-25) and over 100-fold selectivity compared to other histone methyltransferases and non-epigenetic targets. It inhibits the methylation of MED12 in cells with an IC50 of 43 nM.
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Target
Histone Methyltransferase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2080285
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Purity
0.9907
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Molecular Formula
C28H34N4O2
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Molecular Weight
458.6
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SMILES
CNCCN1CCC(CC1)c1cc(CN(C)C(=O)c2cccc(Oc3ccccc3)c2)ccn1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound