TP-110 - CAS 688737-95-3

TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases.

Others

Others

688639

C37H41N3O6

623.74

C(C(N[C@@H](CC1=CC=C(OC)C=C1)C(N[C@H](C(NC(CC2=CC=C(OC)C=C2)C=O)=O)C(C)C)=O)=O)C=3C4=C(C=CC3)C=CC=C4

-20°C

Ice Packs

Small Compound