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Molfinity

TP0427736 - CAS 864374-00-5

TP0427736 - CAS 864374-00-5

MF-0012683-01

$103.81 USD
$103.81 USD
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Product Details

  • Bioactivity

    TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-β-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse hair follicles.

  • Target

    TGF-beta/Smad

  • Related Pathways

    Stem Cells

  • CAS Number

    864374-00-5

  • Purity

    0.9767

  • Molecular Formula

    C14H10N4S2

  • Molecular Weight

    298.39

  • SMILES

    CC=1N=C(C2=C(NC=N2)C=3C=C4C(=CC3)N=CS4)SC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound