TP0480066 - CAS 2245693-15-4

TP0480066, a selective topoisomerase II inhibitor, demonstrates excellent inhibitory activity against DNA gyrase (IC50 = 1.10 nM) and topo IV (IC50 = 62.89 nM) . This compound exhibits potent efficacy against multiple bacterial species, including drug-resistant strains. Moreover, TP0480066 displays significant inhibitory activity against N. gonorrhoeae, making it suitable for research on gonorrhea [1] [2].

Others, Topoisomerase, Antibacterial

Microbiology/Virology, Others, DNA Damage/DNA Repair

2245674

C18H14FN3O5

371.32

N(C)C1=C2C(C(O)=C(C(NC3=CC=C(C(O)=O)C=C3)=O)C(=O)N2)=CC(F)=C1

-20°C

Ice Packs

Small Compound