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TP4 (Nile tilapia piscidin) - CAS 1429184-62-2

TP4 (Nile tilapia piscidin) - CAS 1429184-62-2

SKU:MF-0157846-01

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  • Bioactivity

    TP4 (Nile tilapia piscidin) is an orally active, piscidin-like antimicrobial peptide that inhibits various gram-positive and gram-negative bacterial strains with a minimum inhibitory concentration (MIC) ranging from 0.03 to 10 μg/mL. It demonstrates hemolytic activity and promotes immune response, antioxidant activity, and intestinal health in the presence of bacterial infections. Additionally, TP4 has an anti-tumor effect and induces necrosis in cancer cells by triggering mitochondrial dysfunction [1] [2] [3].

  • Target

    Antibacterial, Necroptosis

  • Related Pathways

    Apoptosis, Microbiology/Virology

  • CAS Number

    1429120

  • Molecular Formula

    C135H226N50O27

  • Molecular Weight

    2981.56

  • SMILES

    [C@@H](CC1=CN=CN1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CC3=CC=CC=C3)N)=O)[C@H](CC)C)=O)=O)C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCCCN)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide