TP53 neoepitope - CAS 151808-74-1

TP53 neoepitope is a high-affinity antigen peptide that targets HLA-A and is capable of activating CD8+ T cell-mediated cytotoxicity against TP53-mutant tumor cells. It holds promise for research involving solid tumors harboring TP53 hotspot mutations (such as R175H, R273H) .

MHC

Immunology/Inflammation

151808-74-1

C45H74N16O13S2

1111.3

[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CCSC)=O)[C@@H](C)O)=O)CCC(O)=O)=O)C(C)C)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(O)=O)CS)=O

-20°C

Ice Packs

Peptide