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Molfinity

TPN171 - CAS 1229018-87-4

TPN171 - CAS 1229018-87-4

SKU:MF-0019142-01

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  • Bioactivity

    TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH) . TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.

  • Target

    PDE

  • Related Pathways

    Metabolism

  • CAS Number

    1228927

  • Purity

    >99.99%

  • Molecular Formula

    C24H35N5O3

  • Molecular Weight

    441.57

  • SMILES

    CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound