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TR-100 - CAS 1128165-86-5
TR-100 - CAS 1128165-86-5
SKU:MF-0117409-01
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Product Details
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Bioactivity
TR-100 is a small molecule inhibitor targeting tumor-associated tropomyosin (Tpm) . It binds to the C-terminus of Tpm3.1, affecting its interaction with actin filaments and thus influencing their stability and function. This mechanism allows TR-100 to specifically affect actin filament bundles in cancer cells without impairing cardiac muscle function. TR-100 is useful for studying the role of Tpm3.1 in cancer cell proliferation and survival, as well as its impact on insulin-stimulated glucose uptake and insulin secretion.
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Target
Arp2/3 Complex
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Related Pathways
Cytoskeletal Signaling
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CAS Number
1128074
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Molecular Formula
C26H38N4O
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Molecular Weight
422.61
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SMILES
N#CC(=CC=1C=2C=CC=CC2N(C1C)CCCN(C)C)C(=O)NCCCCCCCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound