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Molfinity

TR-100 - CAS 1128165-86-5

TR-100 - CAS 1128165-86-5

SKU:MF-0117409-01

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  • Bioactivity

    TR-100 is a small molecule inhibitor targeting tumor-associated tropomyosin (Tpm) . It binds to the C-terminus of Tpm3.1, affecting its interaction with actin filaments and thus influencing their stability and function. This mechanism allows TR-100 to specifically affect actin filament bundles in cancer cells without impairing cardiac muscle function. TR-100 is useful for studying the role of Tpm3.1 in cancer cell proliferation and survival, as well as its impact on insulin-stimulated glucose uptake and insulin secretion.

  • Target

    Arp2/3 Complex

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    1128074

  • Molecular Formula

    C26H38N4O

  • Molecular Weight

    422.61

  • SMILES

    N#CC(=CC=1C=2C=CC=CC2N(C1C)CCCN(C)C)C(=O)NCCCCCCCC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound