TRAM-34 - CAS 289905-88-0

TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34 (TRAM 34) is 200 to 1500-fold than other ion channels.

Potassium Channel, IκB/IKK

NF-κB, Membrane transporter/Ion channel

289817

0.9991

C22H17ClN2

344.84

ClC1=C(C=CC=C1)C(N1C=CC=N1)(C1=CC=CC=C1)C1=CC=CC=C1

-20°C

Ice Packs

Small Compound