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Tretazicar - CAS 21919-05-1

Tretazicar - CAS 21919-05-1

SKU:MF-0094022-01

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  • Bioactivity

    CB1954 (Tretazicar (NSC-115829) ), an anticancer prodrug, is activated by NAD (P) H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.

  • Target

    DNA Alkylator/Crosslinker, Reductase, DNA Alkylation

  • Related Pathways

    Metabolism, DNA Damage/DNA Repair, Endocrinology/Hormones

  • CAS Number

    21919-05-1

  • Purity

    0.997

  • Molecular Formula

    C9H8N4O5

  • Molecular Weight

    252.18

  • SMILES

    NC(=O)c1cc(N2CC2)c(cc1[N+]([O-])=O)[N+]([O-])=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound