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TREX1-IN-3 - CAS 2588445-13-8
TREX1-IN-3 - CAS 2588445-13-8
SKU:MF-0113665-01
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Product Details
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Bioactivity
TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.
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Target
DNA/RNA Synthesis
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
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CAS Number
2588424
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Molecular Formula
C24H19ClN6O4
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Molecular Weight
490.898
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SMILES
[C@@H](N(C)C1=NC(C(NC=2C=NOC2)=O)=C(O)C(=O)N1C)(C3=CC(C#N)=CC=C3)C4=C(Cl)C=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound