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TREX1-IN-4 - CAS 2588445-14-9
TREX1-IN-4 - CAS 2588445-14-9
SKU:MF-0113625-01
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Product Details
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Bioactivity
TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.
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Target
DNA/RNA Synthesis
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
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CAS Number
2588422
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Molecular Formula
C24H19ClN6O4
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Molecular Weight
490.898
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SMILES
[C@H](N(C)C1=NC(C(NC=2C=NOC2)=O)=C(O)C(=O)N1C)(C3=CC(C#N)=CC=C3)C4=C(Cl)C=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound