Tri-GalNAc-DBCO - CAS 2999748-27-3

Tri-GalNAc-DBCO is a PIP-GalNAc coupling compound that binds ASGPR to drive protein down-regulation and target compounds for protein degradation via copper-free strain-promoted azide-alkyne cycloaddition coupled to azide on a non-specifically labeled antibody.

PROTACs, LYTACs

PROTAC

2999718

0.9992

C82H127N11O29

1730.94

CC(=O)N[C@H]1C(OCCCCC(=O)NCCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCOC2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@H](O)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)CCCCC(=O)N2Cc3ccccc3C#Cc3ccccc32)O[C@H](CO)[C@H](O)[C@@H]1O

-20°C

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PROTAC