Tri-GalNAc-NHS ester - CAS 1953146-83-2

Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal targeting receptor expressed on liver cells. This compound is utilized as a protein degrader in LYTAC research [1].

LYTACs

PROTAC

1953146-83-2

C79H137N11O37

1832.98

C(NC(CCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)=O)=O)COCCC(NCCCNC(CCCCO[C@H]4[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O4)=O)=O

-20°C

Ice Packs

PROTAC