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Triapine hydrochloride - CAS 216240-62-9
Triapine hydrochloride - CAS 216240-62-9
SKU:MF-0121475-01
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Product Details
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Bioactivity
Triapine (hydrochloride), also known as 3-AP or PAN-811, represents the hydrochloride variant of Triapine. This compound serves as a potent inhibitor of the M2 subunit of ribonucleotide reductase (RR) and acts as an effective radiosensitizer [1].
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Target
DNA/RNA Synthesis
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
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CAS Number
216240-62-9
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Molecular Formula
C7H10ClN5S
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Molecular Weight
231.71
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SMILES
C(=NNC(N)=S)C1=C(N)C=CC=N1.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound