Triciferol - CAS 957214-00-5

Triciferol acts as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC 50 =87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Triciferol also exhibits efficacious antiproliferative and cytotoxic activities in cancer cell models in vitro [1].

Others, Vitamin, HDAC

DNA Damage/DNA Repair, Metabolism, Chromatin/Epigenetic, Others

957214-00-5

C26H39NO4

429.591

[H][C@@]12CC[C@H]([C@H](C)\C=C(/C)\C=C\C(=O)NO)[C@@]1(C)CCC\C2=C/C=C1C[C@@H](O)C[C@H](O)C1

-20°C

Ice Packs

Small Compound