Trifluridine - CAS 70-00-8

Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

Autophagy, Nucleoside Antimetabolite/Analog, Apoptosis, HSV, DNA/RNA Synthesis, Virus Protease

Apoptosis, Autophagy, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Microbiology/Virology

70-00-8

0.9982

C10H11F3N2O5

296.2

O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(F)(F)F)C(=O)N1

-20°C

Ice Packs

Small Compound