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Trilaciclib - CAS 1374743-00-6
Trilaciclib - CAS 1374743-00-6
SKU:MF-0031261-01
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$33.17 USD
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$33.17 USD
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Product Details
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Bioactivity
Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM respectively. It transiently and reversibly induces G1 cell cycle arrest, mitigates chemotherapy-induced myelosuppression, and enhances antitumour immunity, making it applicable across multiple cancers.
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Target
Cell Cycle Arrest, CDK
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Related Pathways
Cell Cycle/Checkpoint
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CAS Number
1374743-00-6
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Purity
0.99624
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Molecular Formula
C24H30N8O
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Molecular Weight
446.55
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SMILES
CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound