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Trimelamol - CAS 64124-21-6
Trimelamol - CAS 64124-21-6
SKU:MF-0118572-01
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Product Details
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Bioactivity
Trimelamol (CB10-375; NSC283162) is an efficient acid-catalyzed DNA interstrand cross-linker with low neurotoxicity due to its limited penetration of the blood-brain barrier. It exhibits antitumor activity and can overcome platinum resistance. Trimelamol is utilized in research concerning lung and ovarian cancers.
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Target
DNA Alkylator/Crosslinker
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Related Pathways
DNA Damage/DNA Repair
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CAS Number
64097
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Molecular Formula
C9H18N6O3
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Molecular Weight
258.28
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SMILES
OCN(C=1N=C(N=C(N1)N(C)CO)N(C)CO)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound