Trimetrexate glucuronate - CAS 82952-64-5

Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, blocking the synthesis of purine nucleotides and thymidylic acid, therefore affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects.

Antibacterial, Antifolate, Others

Cell Cycle/Checkpoint, Others, Microbiology/Virology

82883

C25H33N5O10

563.564

O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O.COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

-20°C

Ice Packs

Small Compound