Trimipramine N-oxide - CAS 14171-70-1

Trimipramine N-oxide, an active metabolite of the tricyclic antidepressant trimipramine, effectively inhibits human monoamine transporters for noradrenaline (hNAT), serotonin (hSERT), dopamine (hDAT), and the human organic cation transporters (hOCT1 and hOCT2), with IC50 values of 11.7, 3.59, 9.4, 9.35, and 27.4 nM, respectively. It is utilized in the research of depression and anxiety [1].

Others, Drug Metabolite

Metabolism, Others

14100

C20H26N2O

310.43

CC(CN1c2ccccc2CCc2ccccc12)CN(C)(C)=O

-20°C

Ice Packs

Small Compound