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Molfinity

Tripolin B - CAS 186611-44-9

Tripolin B - CAS 186611-44-9

MF-0116264-01

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Product Details

  • Bioactivity

    Tripolin B is an ATP-competitive inhibitor of Aurora kinases, with IC50 values of 2.5 μM and 6 μM for Aurora A and Aurora B kinases, respectively. However, it exhibits no inhibitory effect within cells.

  • Target

    Aurora Kinase

  • Related Pathways

    Chromatin/Epigenetic, Cell Cycle/Checkpoint

  • CAS Number

    186558

  • Molecular Formula

    C12H9N3O

  • Molecular Weight

    211.22

  • SMILES

    O=C1NC=2C=CC=CC2C1=CC3=CN=CN3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound