Triptolide - CAS 38748-32-2

Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation. Triptolide exhibits immunosuppressive, anti-rheumatic, anti-inflammatory, anti-proliferative and anti-tumor activities.

Mdm2, HSP, Apoptosis, NF-κB

Metabolism, NF-κB, Apoptosis, Cytoskeletal Signaling

38714

0.9997

C20H24O6

360.4

[H][C@@]12C[C@@H]3O[C@@]33[C@H](O)[C@]4(O[C@H]4[C@@H]4O[C@]34[C@@]1(C)CCC1=C2COC1=O)C(C)C

-20°C

Ice Packs

Natural Product