Trk-IN-20 - CAS 2460924-63-2

Trk-IN-20 is a 3-vinylindazole derivative compound that effectively inhibits the functions of Trk kinases. It accomplishes this by suppressing the phosphorylation of TrkA, TrkB, and TrkC, with IC50 values of 1.6 nM, 2.9 nM, and 2.0 nM, respectively [1].

Trk receptor, Others

Others, Tyrosine Kinase/Adaptors

2460859

C22H18F2N4

376.4

C(=C/C1=CC=CC=N1)\C=2C=3C(NN2)=CC=C(N[C@H](C)C4=CC(F)=CC(F)=C4)C3

-20°C

Ice Packs

Small Compound