Trk-IN-9 - CAS 2758623-12-8

Trk-IN-9 (Compound 12) is a potent inhibitor of TRK that inhibits the proliferation of Km-12 cell lines and induces apoptosis in a concentration-dependent manner. It also inhibits TRK phosphorylation and blocks downstream pathways, showing potential for NTRK fusion cancer research.

Apoptosis, Trk receptor

Tyrosine Kinase/Adaptors, Apoptosis

2758603

0.9815

C23H24ClFN6O

454.93

N(C=1N=C(NCC2=CC(F)=CC=C2)C(Cl)=CN1)C3=CC(C(N[C@@H]4CCCNC4)=O)=CC=C3

-20°C

Ice Packs

Small Compound