TRPC antagonist 1 - CAS 3027139-12-1

TRPC antagonist1 (compound 15g) is a potent TRP channel (TRPC) antagonist with IC50 values of 2.4 μM, 12.2 μM, 7.6 μM, 2.9 μM, and 3.4 μM for TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, respectively. It demonstrates significant anti-glioblastoma efficacy in vitro against the U87 cell line.

TRP/TRPV Channel

Membrane transporter/Ion channel

3027126

C23H22N4O2S

418.51

O=C(NC1=CC=C(O)C=C1)C=2N=C(SC2)N(CC=3C=CC=4C=CC=CC4C3)CCN

-20°C

Ice Packs

Small Compound