TRPV2-selective blocker 1 - CAS 2242724-49-6

TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, with an IC50 value of 6.3 μM, specifically targeting the TRPV2 channel without affecting TRPV1, TRPV3, or TRPV4 channels, and effectively suppresses TRPV2-mediated calcium influx in macrophages, inhibiting their phagocytic activity [1].

TRP/TRPV Channel, Others

Others, Membrane transporter/Ion channel

2242724-49-6

C15H18OS2

278.43

O=C(C)CC(C(=C1SCCS1)C=2C=CC=CC2)C

-20°C

Ice Packs

Small Compound