Tryptoquivaline D - CAS 60676-56-4

Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 μM. Tryptoquivaline D (1-100 μM), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.

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60676-56-4

C28H28N4O7

532.553

CC(C)[C@@H](OC(C)=O)c1nc2ccccc2c(=O)n1[C@H]1C[C@]2(OC1=O)[C@H]1N(O)[C@H](C)C(=O)N1c1ccccc21

-20°C

Ice Packs

Small Compound