TS-002266 - CAS 2702325-64-0

TS-0022666 is a selective TUT4/7 inhibitor exhibiting antiproliferative and anti-leukaemic activity in vivo and in vitro. It enhances THP-1 cell sensitivity to BCL-2 inhibition, reduces uridylation, and may be used to study cancers with FOCAD deficiency.

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

2702261

0.9818

C31H32Cl2N6O5

639.53

O=C1C=2C(N(C=C1C(O)=O)C=3C=CC(=NC3)N4CC(N(C)C)C4)=CC(=C(Cl)C2)N5[C@@H](COC6=C(Cl)C(OC)=CC=N6)CCC5

-20°C

Ice Packs

Small Compound