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Molfinity

TS-IN-2 - CAS 2945983-00-4

TS-IN-2 - CAS 2945983-00-4

MF-0121481-01

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Product Details

  • Bioactivity

    TS-IN-2 (compound 17), a potent thymidylate synthase (TS) inhibitor, exhibits an IC50 value of 0.81 μM. It promotes apoptosis in cancer cells, induces cell cycle arrest at the S phase, and inhibits DNA synthesis, leading to DNA damage [1].

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    2945983-00-4

  • Molecular Formula

    C18H23N3O4S

  • Molecular Weight

    377.46

  • SMILES

    C(N1N=C(COC2=C(OC)C=C(CC=C)C=C2)OC1=S)N3CCOCC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound