TSPO ligand-3 - CAS 2241669-89-4

TSPO ligand-3, functioning as an AUTAC2 ligand, incorporates both a p-fluorobenzylguanine (FBnG) and a synthetic ligand of FKBP (SLF) moiety, leading to the substantial inhibition of FKBP12 in HeLa cells [1].

AUTACs

PROTAC

2241669-89-4

C34H44N2O9

624.72

[C@@H](OC(=O)C1N(C(C(C(CC)(C)C)=O)=O)CCCC1)(CCC2=CC(OC)=C(OC)C=C2)C3=CC(NC(CCC(O)=O)=O)=CC=C3

-20°C

Ice Packs

PROTAC